MutS as a tool for mutation detection.
نویسندگان
چکیده
منابع مشابه
MutS as a tool for mutation detection.
MutS, a DNA mismatch-binding protein, seems to be a promising tool for mutation detection. We present three MutS based approaches to the detection of point mutations: DNA retardation, protection of mismatched DNA against exonuclease digestion, and chimeric MutS proteins. DNA retardation in polyacrylamide gels stained with SYBR-Gold allows mutation detection using 1-3 microg of Thermus thermophi...
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ژورنال
عنوان ژورنال: Acta Biochimica Polonica
سال: 2005
ISSN: 1734-154X,0001-527X
DOI: 10.18388/abp.2005_3417